McKinsey on Agentic AI: How to Create Business Value

Guest: Alexander Sukharevsky, Global Leader, QuantumBlack, McKinsey
Episode: 922
CXOTalk episode 922 explores why so much AI investment has produced limited measurable business value, and what leaders must change to capture value from agentic AI.

Box CEO Aaron Levie: CIO Advice on Agentic AI and the Enterprise

Guest: Aaron Levie, Chief Executive Officer and Co-Founder, Box
Episode: 921
AI agents work in demos but stall in production, break existing permission models, and run up costs that CIOs never planned for in traditional IT budgets.

Mozilla CTO: Open Source AI Agents and the Fight for Control

Guest: Raffi Krikorian, Chief Technology Officer, Mozilla
Episode: 920
AI agents have become essential enterprise tools.

CIO Playbook: Agentic AI in the Enterprise

Guest: Tim Crawford, CIO Strategic Advisor, AVOA; Anthony Scriffignano, Distinguished Fellow, The Stimson Center
Episode: 919
Agentic AI is changing what CIOs are accountable for.

Autonomous Software Development at Enterprise Scale: Inside a 1,000-Developer Pilot (with Blitzy)

Guest: Enrique Ibarra, CIO and Head of Business Transformation, GNP Seguros
Episode: 918
AI-driven autonomous software development is transitioning from pilot projects to real production deployments in 2026.

AI-Enabled Software Development: AI coding at Global Scale, with Blitzy

Guest: Kris Tokarzewski, Group Chief Technology and Information Officer, Vitality
Episode: 917
In 2026, insurance technology leaders face an important question: can autonomous development meet the AI determinism, auditability, and quality standards that regulated industries require?

Agentic AI and Enterprise Software in 2026

Guest: Praveen Akkiraju, Managing Director, Insight Partners
Episode: 916
Every enterprise software decision in 2026 now runs through the same question: what does agentic AI actually do to my stack, my costs, and my vendors?

How AI Swarms Weaponize Disinformation

Guest: Daniel Thilo Schroeder, Research Scientist, SINTEF; Jonas R. Kunst, Professor, Communication, BI Norwegian Business School
Episode: 915
Coordinated AI agent swarms can now fabricate grassroots consensus, infiltrate communities, and corrupt enterprise AI training data at scale.

HPE's CFO: Making Agentic AI Work in Finance

Guest: Marie Myers, Executive Vice President and Chief Financial Officer, Hewlett Packard Enterprise (HPE)
Episode: 914
Marie Myers explains how she moved agentic AI from advisory analytics into live finance operations.

AI Agent Governance: Inside the Glean AWARE Framework (with Cvent's CIO and CISO)

Guest: Pradeep Mannakkara, Chief Information Officer, Cvent; Ben Mayrides, Chief Information Security Officer, Cvent
Episode: 913
AI agents are multiplying faster than the governance frameworks meant to control them.

Deloitte CTO on the AI Investment Trap: CIO Advisory 2026

Guest: Bill Briggs, Global Chief Technology Officer, Deloitte
Episode: 912
Deloitte's Chief Technology Officer reveals how the imbalance between AI technology spending and organizational investment is creating a compounding trap.

Former CDC Director: How to Fix Healthcare

Guest: Dr. Tom Frieden, President and CEO, Resolve to Save Lives
Episode: 911
Former CDC Director Dr. Tom Frieden explains what it takes to fix our broken healthcare systems.

The AI Attack Lifecycle: Digital Forensics and Intelligent Threats

Guest: Rob T. Lee, Chief AI Officer and Chief of Research, SANS Institute
Episode: 910
CXOTalk explores how AI is transforming the full cyberattack lifecycle.

CIO Agenda 2026: Delivering on the AI Promise

Guest: Tim Crawford, CIO Strategic Advisor, AVOA; Isaac Sacolick, President and Founder, StarCIO
Episode: 909
Learn why most organizations struggle to generate measurable value from AI.

Intelligent Orchestration: Software Delivery for the AI Era, with CEO of GitLab

Guest: Bill Staples, Chief Executive Officer, GitLab
Episode: 908
GitLab CEO explains the paradox of AI coding tools accelerating code writing while slowing overall software delivery.

AI and Collective Intelligence for Smarter Decision-Making

Guest: Alex "Sandy" Pentland, Center Fellow, Human-Centered AI, Stanford University
Episode: 907
Sandy Pentland explains how AI helps leaders make better decisions.

U.S. Bank's Chief AI Officer on Strategy, Governance, and Scaling AI

Guest: Prashant Mehrotra, Executive Vice President and Chief AI Officer, U.S. Bank
Episode: 906
Prashant Mehrotra explains how the bank evaluates AI initiatives.

Robots & Physical AI: EXPLAINED

Guest: Burkhard Böckem, Chief Technology Officer, Hexagon
Episode: 905
Burkhard Boeckem explores what it takes to deploy autonomous systems when failure isn't an option.

Cybersecurity and Quantum Computing: A Readiness Guide

Guest: Anand Oswal, EVP and General Manager, Palo Alto Networks
Episode: 904
Anand Oswal explains the urgent threat that quantum computing poses to global encryption.

Snowflake's EVP of Product Talks Hard Truths on Agentic AI: Readiness, Governance, and AI Economics

Guest: Christian Kleinerman, Executive Vice President of Product, Snowflake
Episode: 903
Christian Kleinerman reveals why AI agents fail when faced with messy enterprise data and governance gaps.